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Clonal Megakaryocyte Dysplasia with Isolated Thrombocytosis Is a Distinct Myeloproliferative Neoplasm Phenotype.

Acta haematologica - 1 Jan 2023

Barosi Giovanni, Campanelli Rita, Massa Margherita, Catarsi Paolo, Carolei Adriana, Abbà Carlotta, Villani Laura, Magrini Umberto, Gregato Giuliana, Bertolini Francesco, de Silvestri Annalisa, Gale Robert Peter, Rosti Vittorio

Abstract excerpt

INTRODUCTION: About 15% of people with a myeloproliferative neoplasm (MPN) are identified as MPN, unclassifiable using the 2016 WHO classification. METHODS: We tested whether persons with platelet concentration ≥450 × 10E+9/L, bone marrow megakaryocyte morphology typical of prefibrotic/early myelofibrosis (pre-MF), and no minor criteria of pre-MF should be classified as a distinct MPN subtype, clonal...

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PMID: 36349787
DOI: 10.1159/000527284

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