Article
Essential thrombocythemia: 2024 update on diagnosis, risk stratification, and management.
American journal of hematology - 1 Apr 2024
Tefferi Ayalew, Vannucchi Alessandro Maria, Barbui Tiziano
Abstract excerpt
OVERVIEW: Essential thrombocythemia is a Janus kinase 2 (JAK2) mutation-prevalent myeloproliferative neoplasm characterized by clonal thrombocytosis; clinical course is often indolent but might be interrupted by thrombotic or hemorrhagic complications, microcirculatory symptoms (e.g., headaches, lightheadedness, and acral paresthesias), and, less frequently, by disease transformation into myelofibrosis (MF) or...
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