Article
[Clonal hematopoiesis and its evolution of myeloproliferative neoplasms].
Zhonghua yi xue za zhi - 5 Dec 2023
Zhang L, Dong H
Abstract excerpt
The mutations of myeloproliferative neoplasma (MPN) mainly include driver mutations and non-driver mutations. The driver mutations mainly include JAK2 mutations, CALR mutations and MPL mutations and non-driver mutations mainly include ASXL1, DNMT3A, TET2, SF3B1, EZH2, TP53, SRSF2, USAF1, etc. Driver and non-driver mutations and their clonal evolution affect the thrombosis and disease transformation of MPN. Clonal...
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