Article
Pathological and genomic features of myeloproliferative neoplasms associated with splanchnic vein thrombosis in a single-center cohort.
Annals of hematology - 1 Jun 2023
Cattaneo Daniele, Bucelli Cristina, Marchetti Alfredo, Lionetti Marta, Fermo Elisa, Bellani Valentina, De Magistris Claudio, Maeda Akihiro, Marella Alessio, Primignani Massimo, Consonni Dario, Gianelli Umberto, Neri Antonino, Baldini Luca, Bolli Niccolò, Iurlo Alessandra
Abstract excerpt
Here, we reviewed clinical-morphological data and investigated mutational profiles by NGS in a single-center series of 58 consecutive MPN-SVT patients admitted to our hospital between January 1979 and November 2021. We identified 15.5% of PV, 13.8% of ET, 34.5% of PMF, 8.6% of SMF and 27.6% of MPN-U. Most cases (84.5%) carried JAK2V617F mutation, while seven patients were characterized by other molecular markers,...
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