Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical and neuroimaging features of familial hemophagocytic lymphohistiocytosis.

Pediatric radiology - 1 Feb 2026

Alkaphoury Mona Gamalludin, Mohammad Shaimaa AbdelSattar, Farghal Noura Bahaa ElDien, Ali Heba Gomaa Abdelraheem, Ragab Iman Ahmed

Abstract excerpt

BACKGROUND: Hemophagocytic lymphohistiocytosis is a non-malignant immune regulation disorder, with activation of uncontrolled inflammatory processes and multiorgan damage; primary hemophagocytic lymphohistiocytosis is genetic. OBJECTIVES: To analyze clinical and brain magnetic resonance imaging features in children with familial hemophagocytic lymphohistiocytosis. MATERIALS AND METHODS: This retrospective study...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Brain
Share to Child

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Infant

Share to Lymphohistiocytosis, Hemophagocytic

Share to Magnetic Resonance Imaging

Share to Neuroimaging

Source

Open in PubMed Open full text

Identifiers

PMID: 41251694
DOI: 10.1007/s00247-025-06454-5
PMCID: PMC12881011

Genes

RAB27A
UNC13D

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical and neuroimaging features of familial hemophagocytic lymphohistiocytosis.PMID 41251694Read ↗

Neuroinflammatory Disease as an Isolated Manifestation of Hemophagocytic Lymphohistiocytosis.Semantic proximity Read ↗

Pediatric hemophagocytic lymphohistiocytosis.Semantic proximity Read ↗

Neurological symptoms of familial hemophagocytic lymphohistiocytosis type 2.Semantic proximity Read ↗

Hemophagocytic lymphohistiocytosis with isolated central nervous system reactivation and optic nerve involvement.Semantic proximity Read ↗

Familial hemophagocytic lymphohistiocytosis in a pediatric patient diagnosed by brain magnetic resonance imaging.Semantic proximity Read ↗

Diagnostic challenges in a child with familial hemophagocytic lymphohistiocytosis type 3 (FHLH3) presenting with fulminant neurological disease.Semantic proximity Read ↗

Familial hemophagocytic phohistiocytosis induced by PRF1 mutation with neurologic manifestations as the initial clinical presentations: A case report.Semantic proximity Read ↗

Allogeneic hematopoietic stem cell transplant for familial hemophagocytic lymphohistiocytosis: a case report and literature review.Semantic proximity Read ↗

Approaching hemophagocytic lymphohistiocytosis.Semantic proximity Read ↗

Hemophagocytic Lymphohistiocytosis in Adolescents and Young Adults: Genetic Predisposition and Secondary Disease.Semantic proximity Read ↗

Contemporary diagnostic methods for hemophagocytic lymphohistiocytic disorders.Semantic proximity Read ↗

Prognostic Factors and Long-term Outcomes in 41 Children With Primary Hemophagocytic Lymphohistiocytosis: Report of a Single-center Experience and Review of the Literature.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.