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Article

Approaching hemophagocytic lymphohistiocytosis.

Frontiers in immunology - 1 Jan 2023

Chinnici Aurora, Beneforti Linda, Pegoraro Francesco, Trambusti Irene, Tondo Annalisa, Favre Claudio, Coniglio Maria Luisa, Sieni Elena

Abstract excerpt

Hemophagocytic Lymphohistiocytosis (HLH) is a rare clinical condition characterized by sustained but ineffective immune system activation, leading to severe and systemic hyperinflammation. It may occur as a genetic or sporadic condition, often triggered by an infection. The multifaceted pathogenesis results in a wide range of non-specific signs and symptoms, hampering early recognition. Despite a great...

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Identifiers

PMID: 37426667
DOI: 10.3389/fimmu.2023.1210041
PMCID: PMC10324660

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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