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Article

Contemporary diagnostic methods for hemophagocytic lymphohistiocytic disorders.

Journal of immunological methods - 1 Feb 2011

Johnson Theodore S, Villanueva Joyce, Filipovich Alexandra H, Marsh Rebecca A, Bleesing Jack J

Abstract excerpt

Hemophagocytic lymphohistiocytosis is a life-threatening multi-system hyperinflammatory disorder characterized by dysfunctional cytolytic lymphocyte responses, hypercytokinemia, and widespread lymphohistiocytic tissue infiltration and destruction. Diagnosis and definitive therapy are often delayed as clinical efforts are directed toward treatment of presumed overwhelming infection. Sporadic cases occur in...

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Identifiers

PMID: 21110979
DOI: 10.1016/j.jim.2010.11.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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