Article
Pediatric hemophagocytic lymphohistiocytosis.
Blood - 16 Apr 2020
Canna Scott W, Marsh Rebecca A
Abstract excerpt
Hemophagocytic lymphohistiocytosis (HLH) is a syndrome describing patients with severe systemic hyperinflammation. Characteristic features include unremitting fever, cytopenias, hepatosplenomegaly, and elevation of typical HLH biomarkers. Patients can develop hepatitis, coagulopathy, liver failure, central nervous system involvement, multiorgan failure, and other manifestations. The syndrome has a high mortality...
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