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Article

Familial hemophagocytic lymphohistiocytosis in a pediatric patient diagnosed by brain magnetic resonance imaging.

Neuropediatrics - 1 Oct 2011

van Egmond M E, Vermeulen R J, Peeters-Scholte C M P C D, Augoustides-Savvopoulou P, Abbink F, Boelens J J, van der Knaap M S

Abstract excerpt

Familial hemophagocytic lymphohistiocytosis (fHLH) is an autosomal recessive disorder characterized by proliferation and infiltration of several organs by activated lymphocytes and macrophages. Without allogeneic stem cell transplantation, fHLH is fatal. We describe a previously healthy 11-month-old boy with a rapidly progressive encephalopathy. An older brother died at 8 months following a subacute...

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PMID: 21959744
DOI: 10.1055/s-0031-1287788

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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