Article
Provider perceptions and insights on polygenic risk scores for colorectal cancer: A qualitative study.
Journal of genetic counseling - 1 Dec 2025
Esmundo Shenazar, Caceres Nenette, Ricker Charité, Idos Gregory E, Loroña Nicole C, Castellon-Lopez Yelba, Schmit Stephanie L, Meade Cathy D, Gwede Clement K, Nguyen Nathalie T, Figueiredo Jane C
Abstract excerpt
Polygenic risk scores (PRS), a measure that sums multiple common genetic susceptibility variants into a single burden measure, can help identify individuals at higher risk for colorectal cancer (CRC). Consequently, there is growing interest in its potential use to guide screening practices, despite the current lack of evidence-based guidelines on the clinical utility of PRS models. Therefore, there is a need to...
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