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Article

Standardization, Education, and Resourcing: The Way Forward for Implementing Polygenic Risk Scores in Hereditary Breast and Ovarian Cancer.

Clinical and translational science - 1 Aug 2025

Purvis Rebecca, Taylor Natalie, Young Mary-Anne, James Paul, Forrest Laura E

Abstract excerpt

The clinical utility and implementation of polygenic risk scores (PRS) in the setting of personalized risk assessment for hereditary breast and ovarian cancer (HBOC) continues to be investigated. We aimed to explore and analyze genetic healthcare providers' perspectives toward national implementation in Australia, acknowledging the vitality of provider knowledge, priorities, and support. A two-phase exploratory,...

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Identifiers

PMID: 40836576
DOI: 10.1111/cts.70323
PMCID: PMC12368281

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