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Article

Genomic determinants of the diffusely infiltrative gliomatosis cerebri phenotype.

Journal of neuro-oncology - 16 Oct 2025

Dasgupta Pushan, Dagher Samir A, Chi Xiaohan, Soomro Zaid, Bhat Surya, Campbell Erick, Wintermark Max, Puduvalli Vinay K, Lin Ruitao, Chen Melissa M, Majd Nazanin K

Abstract excerpt

PURPOSE: Gliomatosis cerebri (GC) is defined as a diffusely infiltrative pattern of growth affecting at least three contiguous lobes of the brain. GC presents unique challenges in terms of surgery and radiation therapy. We evaluated the genomic determinants of GC. METHODS: In this retrospective study, we evaluated genetic alterations and overall (OS) and progression-free survival (PFS) durations in...

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PMID: 41099968
DOI: 10.1007/s11060-025-05285-6

Genes

GC
TERT

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