A Novel Type of IDH-wildtype Glioma Characterized by Gliomatosis Cerebri-like Growth Pattern, TERT Promoter Mutation, and Distinct Epigenetic Profile.

doi:10.1097/PAS.0000000000002118

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Article

A Novel Type of IDH-wildtype Glioma Characterized by Gliomatosis Cerebri-like Growth Pattern, TERT Promoter Mutation, and Distinct Epigenetic Profile.

The American journal of surgical pathology - 1 Dec 2023

Muench Amos, Teichmann Daniel, Spille Dorothee, Kuzman Peter, Perez Eilis, May Sven-Axel, Mueller Wolf C, Kombos Theodoros, Nazari-Dehkordi Shokufe, Onken Julia, Vajkoczy Peter, Ntoulias Georgios, Bettencourt Conceição, von Deimling Andreas, Paulus Werner, Heppner Frank L, Koch Arend, Capper David, Kaul David, Thomas Christian, Schweizer Leonille

Abstract excerpt

Diffuse gliomas in adults encompass a heterogenous group of central nervous system neoplasms. In recent years, extensive (epi-)genomic profiling has identified several glioma subgroups characterized by distinct molecular characteristics, most importantly IDH1/2 and histone H3 mutations. A group of 16 diffuse gliomas classified as "adult-type diffuse high-grade glioma, IDH-wildtype, subtype F (HGG-F)" was...

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PMID: 37737691
DOI: 10.1097/PAS.0000000000002118

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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