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Article

Diffuse Gliomas of the Brainstem and Cerebellum in Adults Show Molecular Heterogeneity

16 Feb 2021

Abstract excerpt

Posterior fossa (PF) diffuse gliomas in pediatric patients frequently harbor the H3 K27M mutation. Among adults, PF diffuse gliomas are rare, with limited data regarding molecular features and clinical outcomes. We identified 28 adult PF diffuse glioma patients (17 males; median: 50 y, range: 19 to 78 y), with surgery performed at our institution (13 brainstem; 15 cerebellum). Histologic subtypes included...

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PMID: 33606385
DOI: 10.1097/pas.0000000000001690

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