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Molecular Genetics of Gliomas

1 Jan 2014

Abstract excerpt

Diffusely infiltrating gliomas are the most common primary brain tumors and include astrocytomas, oligodendrogliomas, and oligoastrocytomas of grades II and III and glioblastoma (GBM), grade IV. Histologic classification is increasingly aided by molecular genetic studies, which assist in the diagnosis and provide prognostic and predictive value. Mutations in IDH1 are frequent in grades II and III astrocytomas,...

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PMID: 24445767
DOI: 10.1097/ppo.0000000000000020

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