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Article

Clinical and molecular characteristics of thalamic gliomas in adults: prognostic impact of TERT promoter mutation.

Neurosurgical review - 14 Aug 2026

Tsuzuki Shunsuke, Muragaki Yoshihiro, Nitta Masayuki, Masui Kenta, Komori Takashi, Saito Taiichi, Maruyama Takashi, Koriyama Shunichi, Ro Buntou, Kawamata Takakazu

Abstract excerpt

BACKGROUND: Adult thalamic gliomas (ATGs) are rare and biologically heterogeneous tumors. Although the 2021 World Health Organization (WHO) classification designates all diffuse midline gliomas (DMGs), H3-altered, as grade 4, accumulating evidence suggests that adult thalamic DMGs may exhibit more indolent clinical behavior, compared with glioblastomas or pediatric DMGs. In this study, we aimed to characterize...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42595830
DOI: 10.1007/s10143-026-04447-y
PMCID: PMC13473172

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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