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Article

Reflex somatic testing for the detection of FGFR alterations in urinary tract carcinomas: A dual-institutional experience.

American journal of clinical pathology - 1 Dec 2025

Nguyen Ngoc-Nhu Jennifer, Olkhov-Mitsel Ekaterina, Craddock Kenneth J, Flood Trevor A, Downes Michelle R

Abstract excerpt

OBJECTIVE: To describe the prevalence and clinicopathologic associations of FGFR-altered urinary tract carcinomas in institutions incorporating reflex testing. METHODS: Next-generation sequencing was prospectively performed on urinary tract carcinomas for the detection of FGFR1-4 alterations at 2 tertiary care centers (2021-2025), using the Oncomine Comprehensive Assay (OCA) v3 DNA and OCA Plus RNA. Reflex...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41097827
DOI: 10.1093/ajcp/aqaf108
PMCID: PMC12782305

Genes

FGFR1
FGFR3
FGFR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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