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Routine application of next-generation sequencing testing in uro-oncology-Are we ready for the next step of personalised medicine?

European journal of cancer (Oxford, England : 1990) - 1 Mar 2021

Rodler Severin, Jung Andreas, Greif Philipp A, Rühlmann Katharina, Apfelbeck Maria, Tamalunas Alexander, Kretschmer Alexander, Schulz Gerald B, Szabados Bernadett, Stief Christian, Heinemann Volker, Westphalen Christoph B, Casuscelli Jozefina

Abstract excerpt

AIM OF THE STUDY: Next-generation sequencing (NGS) might represent a valuable diagnostic tool to identify somatic alterations and enable personalised medicine in uro-oncology. We aim to determine feasibility and impact of routine NGS in clinical practice. METHODS: Tumours from patients with genitourinary cancers were subjected to NGS. Results were discussed in a dedicated molecular tumour board. Statistical...

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PMID: 33535139
DOI: 10.1016/j.ejca.2020.12.024

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