Article
Predictive Modeling of DNA Damage Outcomes: Classification of Mutational Determinants Using Augmented Machine Learning Techniques.
Chemical research in toxicology - 17 Nov 2025
Balasubramanian Surabhya, Dayanidhi David, Velmurugan Harini, Rajkumar Kavibharathi, Bhoopalan Ravikumar, Vasagam Swamiraj Nithiyanantha, Vaidyanathan Ganesan Vaidyanathan
Abstract excerpt
The mutational outcome of DNA damage as a direct result of constant chemical assault is governed by major factors, including the structure and nature of damage, replication, and repair machinery in vivo. The role of the size of the adduct, adduct-flanking bases, and the type of polymerase involved in the replication pathway is prominently seen through existing in vitro and in vivo studies. In this work, machine...
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