Article
DNA helicases associated with genetic instability, cancer, and aging.
Advances in experimental medicine and biology - 1 Jan 2013
Suhasini Avvaru N, Brosh Robert M
Abstract excerpt
DNA helicases have essential roles in the maintenance of genomic -stability. They have achieved even greater prominence with the discovery that mutations in human helicase genes are responsible for a variety of genetic disorders and are associated with tumorigenesis. A number of missense mutations in human helicase genes are linked to chromosomal instability diseases characterized by age-related disease or...
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