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Article

HLA DQ2/DQ8 haplotypes and the clinical presentation of patients with celiac disease.

Revista espanola de enfermedades digestivas - 1 Sept 2026

Antunes Alicia, Andrade Fabiana, Kotze Lorete Maria da Silva, Nisihara Renato

Abstract excerpt

Celiac disease (CD) is a chronic condition triggered by gluten consumption in genetically predisposed individuals, with approximately 95% of CD patients carrying the HLA-DQ2 or DQ8 risk haplotypes. In addition to genetic susceptibility, recent evidence suggests that these haplotypes may influence the clinical presentation and severity of CD. However, evidence on this topic remains scarce, and the impact of...

Read the complete abstract on PubMed

Topics

Humans
Celiac Disease
HLA-DQ Antigens
Haplotypes
Female
Male
Adult

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Middle Aged

Adolescent

Young Adult

Genetic Predisposition to Disease

Source

Identifiers

PMID: 41020955
DOI: 10.17235/reed.2025.11541/2025

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 26 Oct 2026.

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