Article
Immunogenetics of Celiac Disease: A Focus on Arab Countries.
Current molecular medicine - 1 Jan 2020
Younes Nadin, Younes Salma, Alsharabasi Ola A, El Zowalaty Mohamed E, Mustafa Ibrahim, Jahromi Mohamed, Uddin Shahab, Al-Nesf Mariam, Pintus Gianfranco, Zayed Hatem
Abstract excerpt
Celiac Disease (CD) is a complex immunogenic disease mainly triggered by gluten intake in genetically susceptible individuals with a prevalence of 1 in 100-300. CD results from the interplay between genetic and environmental factors. Genetic susceptibility is believed to play a prominent role in the pathogenicity of CD, mainly due to human leukocyte antigen (HLA)-related class II genes. Although CD is...
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