Article
Evaluation of HIV-1 DNA resistance evolution in highly treatment-experienced and multi-resistant individuals under suppressive antiretroviral therapy: a longitudinal study from the PRESTIGIO Registry.
The Journal of antimicrobial chemotherapy - 4 Nov 2025
Armenia D, Marchegiani G, Spagnuolo V, Bellocchi M C, Galli L, Clemente T, Carioti L, Lolatto R, Ferrara M, Gagliardini R, Marchetti G C, Torti C, De Socio G, Fornabaio C, Zazzi M, Castagna A, Santoro M M
Abstract excerpt
BACKGROUND: This study aimed to clarify whether resistance detected in HIV-1 DNA might evolve in virologically suppressed highly treatment-experienced (HTE) individuals with multidrug resistance (MDR). METHODS: Twenty-three virologically suppressed HTE MDR individuals from the PRESTIGIO Registry with two longitudinal samples available under virological suppression at two different time points (T0-T1) were...
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- Humans
- HIV-1
- HIV Infections
- Longitudinal Studies
- Male