Article
HIV-1 DNA dynamics and variations in HIV-1 DNA protease and reverse transcriptase sequences in multidrug-resistant patients during successful raltegravir-based therapy.
Journal of medical virology - 1 Dec 2016
Michelini Zuleika, Galluzzo Clementina Maria, Pirillo Maria Franca, Francisci Daniela, Degli Antoni Anna, Vivarelli Angela, Ladisa Nicoletta, Cirioni Oscar, Weimer Liliana Elena, Fragola Vincenzo, Cara Andrea, Floridia Marco, Baroncelli Silvia
Abstract excerpt
There is limited information on the variations of HIV-1 DNA mutation profile in reverse transcriptase (RT) and protease (PR) genes during suppressive antiretroviral treatment (plasma HIV-1 RNA continuously <50 copies/ml) with raltegravir (RAL)-based regimens in patients with baseline RT/PR resist...
Topics
- Adult
- Anti-HIV Agents
- Antiretroviral Therapy, Highly Active
- DNA, Viral
- Drug Resistance, Multiple, Viral
- Female
- Genetic Variation
- Genotype
- HIV Protease
- HIV Reverse Transcriptase
- HIV-1
- Humans
- Male