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HIV-1 Drug Resistance Trends in the Era of Modern Antiretrovirals: 2018–2024

24 Jul 2025

Abstract excerpt

Background: Antiretroviral drug resistance limits treatment options for people with human immunodeficiency virus (HIV) 1 and may reduce the effectiveness of preexposure prophylaxis. Novel treatment options with enhanced efficacy and more convenient formulations have become available from 2016 to 2021. Large-scale studies of trends in the prevalences of plasma RNA drug resistance mutations (DRMs) since 2018 are...

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PMID: 40799780
DOI: 10.1093/ofid/ofaf446

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