Article
Treatment Emergent Dolutegravir Resistance Mutations in Individuals Naïve to HIV-1 Integrase Inhibitors: A Rapid Scoping Review.
Viruses - 15 Sept 2023
Tao Kaiming, Rhee Soo-Yon, Chu Carolyn, Avalos Ava, Ahluwalia Amrit K, Gupta Ravindra K, Jordan Michael R, Shafer Robert W
Abstract excerpt
Background: Dolutegravir (DTG)-based antiretroviral therapy (ART) rarely leads to virological failure (VF) and drug resistance in integrase strand transfer inhibitor (INSTI)-naïve persons living with HIV (PLWH). As a result, limited data are available on INSTI-associated drug resistance mutations (DRMs) selected by DTG-containing ART regimens. Methods: We reviewed studies published through July 2023 to identify...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
