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Article

Prevalence of Low EPHX1 Activity-Associated Genotypes in Himalayan Populations of India.

American journal of human biology : the official journal of the Human Biology Council - 1 Sept 2025

Rai Divya, De Saptaparni, Das Debashruti, Tamang Shishir, Mandal Kumaresh, Subba Soni, Sahithi L Suhasini, Reddy Alla G, Govindaraj Periyasamy, Thangaraj Kumarasamy, Chaubey Gyaneshwer, Tamang Rakesh

Abstract excerpt

OBJECTIVES: The EPHX1 gene encodes human microsomal epoxide hydrolase 1, which helps in biotransformation processes. Its activity is influenced by combinations of genotypes at its polymorphic sites. There are no data on the EPHX1 gene variants in the Indian Himalayan and adjoining populations (HAAPs). Therefore, this study aims to investigate the activity-associated genotypes of the EPHX1 gene variants in the...

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PMID: 40974229
DOI: 10.1002/ajhb.70148

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EPHX1

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