Examining the Effects of Quercetin on Phenotypic Characteristics of Human Mesenchymal Stem Cells

Abstract excerpt

Introduction: A significant obstacle to mesenchymal stem cell (MSC) potency and therapeutic utility is in vitro senescence, an irreversible cessation of replication associated with age-related complications. Senolytic drugs, such as quercetin, may be helpful in selectively culling senescent cells while leaving non-senescent cells unaffected, thereby increasing potency of high-passage MSCs. Methods: The...

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