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Quercetin enhances decidualization through AKT-ERK-p53 signaling and supports a role for senescence in endometriosis

2023-09-02

Abstract excerpt

Quercetin, a flavonoid with senolytic activity, has attracted great interest as a therapy for fibrotic diseases such as pulmonary fibrosis, a disorder attributed to senescent pulmonary fibroblasts. Interestingly, quercetin has shown some benefit in pre-clinical models of endometriosis, an inflammatory condition characterized by senescent endometrial stromal cells and in severe cases, intraperitoneal fibrotic lesio...

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Literature Corpus work
b17fd14b-1e4c-5e2b-91f8-5cef97c27f2c
DOI
10.1101/2023.08.30.23294800
Open publication

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Quercetin enhances decidualization through AKT-ERK-p53 signaling and supports a role for senescence in endometriosisDOI 10.1101/2023.08.30.23294800
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