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Chemical screen identifies a geroprotective role of quercetin in premature aging

1 Aug 2018

Abstract excerpt

Aging increases the risk of various diseases. The main goal of aging research is to find therapies that attenuate aging and alleviate aging-related diseases. In this study, we screened a natural product library for geroprotective compounds using Werner syndrome (WS) human mesenchymal stem cells (hMSCs), a premature aging model that we recently established. Ten candidate compounds were identified and quercetin was...

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PMID: 30069858
DOI: 10.1007/s13238-018-0567-y

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