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Article

Age-related changes in human bone marrow-derived mesenchymal stem cells: consequences for cell therapies.

Mechanisms of ageing and development - 1 Mar 2008

Stolzing A, Jones E, McGonagle D, Scutt A

Abstract excerpt

Human mesenchymal stem cells (hMSC) represent a promising cell-based therapy for a number of degenerative conditions. Understanding the effect of aging on hMSCs is crucial for autologous therapy development in older subject whom degenerative diseases typically afflict. Previous investigations into the effects of aging on hMSC have proved contradictory due to the relative narrow age ranges of subjects assessed and...

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Identifiers

PMID: 18241911
DOI: 10.1016/j.mad.2007.12.002

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MSC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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