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Autophagy-driven modulation of stem cell dynamics in Helicobacter pylori -induced gastric diseases in mice

1 Sept 2025

Abstract excerpt

Chronic Helicobacter pylori infection is a major contributor to gastric disease progression, with its involvement in autophagy and stem cell dynamics playing a critical role in disease mechanisms. This study investigated how H. pylori, particularly in combination with the carcinogen N-nitroso-N-methylurea (NMU), disrupted autophagy and stem cell function, driving gastric pathology. H. pylori infection...

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PMID: 40888366
DOI: 10.1080/21505594.2025.2551176

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