Article
<i>Helicobacter pylori</i> targets cancer-associated apical-junctional constituents in gastroids and gastric epithelial cells
14 Aug 2014
Abstract excerpt
OBJECTIVE: Helicobacter pylori strains that express the oncoprotein CagA augment risk for gastric cancer. However, the precise mechanisms through which cag(+) strains heighten cancer risk have not been fully delineated and model systems that recapitulate the gastric niche are critical for understanding pathogenesis. Gastroids are three-dimensional organ-like structures that provide unique opportunities to study...
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