Article
Aberrant Cytoplasmic p53 Expression and Its Correlation with <italic>TP53</italic> Mutation Status and Functional Implications in Stage II and III Colorectal Cancer.
Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 2026
Kim Meejeong, Jin Lingyan, Jin Hye-Yeong, Cho Nam-Yun, Han Saewon, Kim Tae-You, Bae Jeong Mo, Kang Gyeong Hoon, Kim Younghoon
Abstract excerpt
INTRODUCTION: TP53 mutation is frequently observed in colorectal cancer (CRC) and is often linked to associated with immunohistochemical p53 expression patterns. Recent studies have identified cytoplasmic p53 expression in CRC, but its correlation with TP53 mutation domains and functional properties remains unclear. METHODS: We evaluated nuclear and cytoplasmic p53 staining patterns in 429 stage II and III CRC...
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