Multi-population genome-wide association study identifies multiple novel loci associated with asymptomatic intracranial large artery stenosis.

doi:10.1177/17474930251374471

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Multi-population genome-wide association study identifies multiple novel loci associated with asymptomatic intracranial large artery stenosis.

International journal of stroke : official journal of the International Stroke Society - 1 Apr 2026

Liu Minghua, Khasiyev Farid, Spagnolo-Allende Antonio, Sanchez Danurys L, Andrews Howard, Yang Qiong, Beiser Alexa, Qiao Ye, Romero Jose Rafael, Rundek Tatjana, Brickman Adam M, Manly Jennifer J, Elkind Mitchell Sv, Seshadri Sudha, Chen Christopher, Del Brutto Oscar H, Hilal Saima, Wasserman Bruce A, Tosto Giuseppe, Fornage Myriam, Gutierrez Jose

Abstract excerpt

INTRODUCTION: Intracranial large artery stenosis (ILAS) is one of the most common causes of stroke worldwide and is associated with the risk for future vascular events. Asymptomatic ILAS is a frequent finding on neuroimaging and shares many risk factors with atherosclerotic vascular disease. Whether asymptomatic ILAS is driven by genetic variants is not well-understood. METHODS: This study included 4960...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Constriction, Pathologic

Share to Genetic Loci

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Magnetic Resonance Angiography

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed

Identifiers

PMID: 40851121
DOI: 10.1177/17474930251374471

Genes

DTL
INTS7
LPGAT1
NEK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multi-population genome-wide association study identifies multiple novel loci associated with asymptomatic intracranial large artery stenosis.PMID 40851121Read ↗

Multi-population Genome-Wide Association Study Identifies Multiple Novel Loci associated with Asymptomatic Intracranial Large Artery StenosisSemantic proximity Read ↗

Genetic determinants of intracranial large artery stenosis in the northern Manhattan study.Semantic proximity Read ↗

Genome-Wide Association Study of Intracranial Artery Stenosis Followed by Phenome-Wide Association Study.Semantic proximity Read ↗

Genetic Risk Factors of Intracranial Atherosclerosis.Semantic proximity Read ↗

Genetic susceptibility to cerebrovascular disease: A systematic review.Semantic proximity Read ↗

Common and distinct risk profiles of asymptomatic extra- and intracranial atherosclerosis in the Nagahama cohort.Semantic proximity Read ↗

Intracranial Aneurysms and Genetics: An Extensive Overview of Genomic Variations, Underlying Molecular Dynamics, Inflammatory Indicators, and Forward-Looking InsightsSemantic proximity Read ↗

Identification of Novel Genetic Risk Variants Associated With Early-Onset Ischemic Stroke in Taiwan.Semantic proximity Read ↗

Common variants at 6p21.1 are associated with large artery atherosclerotic stroke.Semantic proximity Read ↗

Genome-wide association analysis identifies new candidate risk loci for familial intracranial aneurysm in the French-Canadian population.Semantic proximity Read ↗

Association studies of candidate single-nucleotide polymorphisms with Symptomatic Intracranial Atherosclerotic Stenosis in a Chinese Han populationSemantic proximity Read ↗

Rare RNF213 variants and the risk of intracranial artery stenosis/occlusion disease in Chinese population: a case-control studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.