Intracranial Arterial Stenosis beyond Atherosclerosis: Insights from RNF213.

Abstract excerpt

Intracranial arterial stenosis is a major cause of ischemic stroke worldwide, particularly in the Asian population. Although traditionally regarded as a manifestation of atherosclerotic disease, increasing evidence suggests that non-atherosclerotic arteriopathies also contribute substantially to its pathogenesis. These conditions, including arterial dissection, inflammatory vasculopathies, and moyamoya disease,...

Topics

• Humans
• Ubiquitin-Protein Ligases
• Atherosclerosis
• Genetic Predisposition to Disease
• Adenosine Triphosphatases
• Constriction, Pathologic