Article
Genetic determinants of intracranial large artery stenosis in the northern Manhattan study.
Journal of the neurological sciences - 15 May 2022
Liu Minghua, Sariya Sanjeev, Khasiyev Farid, Tosto Giuseppe, Dueker Nicole D, Cheung Ying Kuen, Wright Clinton B, Sacco Ralph L, Rundek Tatjana, Elkind Mitchell S V, Gutierrez Jose
Abstract excerpt
BACKGROUND: Intracranial stenosis is one of the most common causes of stroke worldwide. Several single nucleotide polymorphisms have been associated with intracranial atherosclerosis, which is inferred to be the most common underlying cause of intracranial large artery stenosis (ILAS). We previously reviewed known genetic variants related to ILAS in predominantly Asian cohorts, but their prevalence and role in...
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