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Article

Mitochondrial DNA Copy Number and Risk of Gestational Metabolic Disorders: A Two-Sample Mendelian Randomization Study.

American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Aug 2025

Zhan Feng, Yang Huijuan, Li Xuemei, Guo Yina, Wu Jianbo, He Lidan

Abstract excerpt

BACKGROUND: Mitochondrial DNA copy number (mtDNA-CN) has been implicated in gestational metabolic disorders (GMD), yet their causal relationships remain unclear. This study employed genetic approaches to investigate potential causal associations between mtDNA-CN and various GMDs. METHODS: We conducted a two-sample Mendelian randomization (MR) analysis utilizing genome-wide association study (GWAS) summary...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40833289
DOI: 10.1111/aji.70144

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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