Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association Between Whole Blood–Derived Mitochondrial DNA Copy Number, Low‐Density Lipoprotein Cholesterol, and Cardiovascular Disease Risk

7 Oct 2023

Abstract excerpt

Background The relationship between mitochondrial DNA copy number (mtDNA CN) and cardiovascular disease remains elusive. Methods and Results We performed cross‐sectional and prospective association analyses of blood‐derived mtDNA CN and cardiovascular disease outcomes in 27 316 participants in 8 cohorts of multiple racial and ethnic groups with whole‐genome sequencing. We also performed Mendelian randomization to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diet and metabolism studies
Share to Metabolomics and Mass Spectrometry Studies
Share to Mitochondrial Function and Pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37804200
DOI: 10.1161/jaha.122.029090

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association Between Whole Blood–Derived Mitochondrial DNA Copy Number, Low‐Density Lipoprotein Cholesterol, and Cardiovascular Disease RiskPMID 37804200Read ↗

The association between mitochondrial DNA copy number, low-density lipoprotein cholesterol, and cardiovascular disease riskSemantic proximity Read ↗

Low mitochondrial copy number drives atherogenic cardiovascular disease: evidence from prospective cohort analyses in the UK Biobank combined with Mendelian RandomizationSemantic proximity Read ↗

Association of Mitochondrial DNA Copy Number With Cardiovascular DiseaseSemantic proximity Read ↗

Low leukocyte mitochondrial DNA abundance drives atherosclerotic cardiovascular diseases: a cohort and Mendelian randomization study.Semantic proximity Read ↗

Role of mitochondrial DNA copy number in incident cardiovascular diseases and the association between cardiovascular disease and type 2 diabetes: A follow-up study on middle-aged womenSemantic proximity Read ↗

Mitochondrial DNA Copy Number and Risk of Gestational Metabolic Disorders: A Two-Sample Mendelian Randomization Study.Semantic proximity Read ↗

Mitochondrial DNA Copy Number (mtDNA-CN) Can Influence Mortality and Cardiovascular Disease via Methylation of Nuclear DNA CpGsSemantic proximity Read ↗

Genetic analysis of mitochondrial DNA copy number and associated traits identifies loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation, and reveals a causal association of mitochondrial function with mortalitySemantic proximity Read ↗

Evaluation of mitochondrial DNA copy number estimation techniquesSemantic proximity Read ↗

Nuclear genetic control of mtDNA copy number and heteroplasmy in humansSemantic proximity Read ↗

Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation.Semantic proximity Read ↗

Lower mitochondrial DNA abundance in blood cells is associated with higher general morbidity and all-cause mortality: a 30-year prospective epidemiological studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.