Article
Lipids, apolipoproteins and gestational diabetes mellitus: a Mendelian randomization study.
BMC pregnancy and childbirth - 6 May 2024
Shan Dan, Wang Ao, Yi Ke
Abstract excerpt
BACKGROUND: This study investigates the causal relationship between lipid traits and GDM in an effort to better understand the aetiology of GDM. METHODS: Employing a two-sample Mendelian Randomization (MR) framework, we used Single Nucleotide Polymorphisms (SNPs) as instrumental variables to examine the impact of lipids and apolipoproteins on GDM. The research comprised univariable and multivariable MR analyses,...
Topics
- Humans
- Mendelian Randomization Analysis
- Female
- Pregnancy
- Diabetes, Gestational
- Polymorphism, Single Nucleotide
- Triglycerides
- Apolipoprotein A-I
- Cholesterol, HDL
- Apolipoproteins
- Body Mass Index
- Lipids
- Risk Factors