Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polygenic Resistance to Blood Pressure Treatment and Stroke Risk: Insights from the All of Us Research Program.

Annals of neurology - 1 Jan 2026

Huo Shufan, Rivier Cyprien A, Clocchiatti-Tuozzo Santiago, Renedo Daniela, Petersen Nils, de Havenon Adam, Meeker Daniella, Zhao Hongyu, Ohno-Machado Lucila, Sheth Kevin N, Falcone Guido J

Abstract excerpt

OBJECTIVE: Our goal was to investigate the impact of polygenic susceptibility to hypertension on systolic blood pressure (BP), uncontrolled hypertension, and stroke among hypertensive patients with BP treatment prescription. METHODS: This genetic association study used data from the All of Us Research Program (2017-2023) and replicated findings using the United Kingdom Biobank (2006-2010). Participants prescribed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Antihypertensive Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Blood Pressure

Share to Hypertension

Share to Multifactorial Inheritance

Share to Risk Factors

Share to Stroke

Share to United States

Source

Identifiers

PMID: 40827941
DOI: 10.1002/ana.78009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polygenic Resistance to Blood Pressure Treatment and Stroke Risk: Insights from the All of Us Research Program.PMID 40827941Read ↗

Association between genetic risk of high SBP and hypertension control: the CoLaus|PsyColaus study.Semantic proximity Read ↗

Genetics of resistant hypertension: a novel pharmacogenomics phenotype.Semantic proximity Read ↗

Association of Polygenic Susceptibility to Hyperlipidemia With Cholesterol Control and Recurrent Stroke in Ischemic Stroke Survivors.Semantic proximity Read ↗

Blood Pressure and Risk of Cardiovascular Disease in UK Biobank: A Mendelian Randomization Study.Semantic proximity Read ↗

Association of a Multiancestry Genome-Wide Blood Pressure Polygenic Risk Score With Adverse Cardiovascular EventsSemantic proximity Read ↗

Genetically-Determined Low-density Lipoprotein in Ischemic Stroke SurvivorsSemantic proximity Read ↗

A multi-ethnic polygenic risk score is associated with hypertension prevalence and progression throughout adulthood.Semantic proximity Read ↗

Polygenic risk scores predict blood pressure changes independent of dietary intervention: a secondary analysis of the NUPRESS trial.Semantic proximity Read ↗

Polygenic risk scores associate with blood pressure traits across the lifespan.Semantic proximity Read ↗

Associations of genetic susceptibility and healthy lifestyle with incidence of coronary heart disease and stroke in individuals with hypertension.Semantic proximity Read ↗

Human essential hypertension: no significant association of polygenic risk scores with antihypertensive drug responses.Semantic proximity Read ↗

Genetically determined blood pressure, antihypertensive drug classes, and risk of stroke subtypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.