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Article

Polygenic risk scores predict blood pressure changes independent of dietary intervention: a secondary analysis of the NUPRESS trial.

European journal of nutrition - 1 Aug 2026

Holzbach Luciana C, Marcadenti Aline, Bersch-Ferreira Angela C, Machado Rachel H Vieira, Carvalho Ana Paula P F, Pinto Sônia L, Penafort Andreza M, Coelho Alexandre S G, Cominetti Cristiane

Abstract excerpt

PURPOSE: This study aimed to investigate whether genetic variability, assessed through polygenic risk scores (PRSs), predicts blood pressure (BP) changes in individuals with systemic arterial hypertension (SAH), and to explore potential interactions between genetic risk and dietary interventions. METHODS: This study represents a secondary analysis of data from the Brazilian multicentre trial (NUPRESS), which...

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PMID: 42541580
DOI: 10.1007/s00394-026-04072-x
PMCID: PMC13428793

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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