Article
Heterogeneity in association of myocardial injury and mortality in sepsis or acute respiratory distress syndrome by subphenotype: a retrospective study.
Critical care (London, England) - 19 Aug 2025
Sanchez Pablo Amador, Obeidalla Sarah, Kerchberger V Eric, Moore Andrew R, Maddali Manoj V, Kangelaris Kirsten N, Hendrickson Carolyn M, Evrard Bruno, Liu Kathleen D, Bastarache Julie A, Matthay Michael A, Rogers Angela J, Calfee Carolyn S
Abstract excerpt
RATIONALE: Myocardial injury is common in acute respiratory distress syndrome (ARDS) and sepsis and associated with increased mortality. Two latent class analysis derived subphenotypes are associated with differential risk of mortality in these populations, though the association of troponin-I with mortality within each subphenotype is unknown. METHODS: The derivation (n = 597 in EARLI) and validation (n = 452 in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.