Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

tstrait: a quantitative trait simulator for ancestral recombination graphs.

Bioinformatics (Oxford, England) - 3 Jun 2024

Tagami Daiki, Bisschop Gertjan, Kelleher Jerome

Abstract excerpt

SUMMARY: Ancestral recombination graphs (ARGs) encode the ensemble of correlated genealogical trees arising from recombination in a compact and efficient structure and are of fundamental importance in population and statistical genetics. Recent breakthroughs have made it possible to simulate and infer ARGs at biobank scale, and there is now intense interest in using ARG-based methods across a broad range of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Computer Simulation
Share to Genetics, Population
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Phenotype

Share to Quantitative Trait Loci

Share to Recombination, Genetic

Share to Software

Source

Open in PubMed Open full text

Identifiers

PMID: 38796683
DOI: 10.1093/bioinformatics/btae334
PMCID: PMC11784591

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

tstrait: a quantitative trait simulator for ancestral recombination graphs.PMID 38796683Read ↗

Leveraging ancestral recombination graphs for scalable mixed-model analysis of complex traits.Semantic proximity Read ↗

Biobank-scale inference of ancestral recombination graphs enables genealogical analysis of complex traits.Semantic proximity Read ↗

Genetic prediction with ARG-powered linear algebra.Semantic proximity Read ↗

Mapping trait loci by use of inferred ancestral recombination graphs.Semantic proximity Read ↗

Association mapping of complex diseases with ancestral recombination graphs: models and efficient algorithms.Semantic proximity Read ↗

GeneEvolve: a fast and memory efficient forward-time simulator of realistic whole-genome sequence and SNP data.Semantic proximity Read ↗

Tracing the evolutionary histories of ultra-rare variants using variational dating of large ancestral recombination graphsSemantic proximity Read ↗

Evaluation of methods for estimating coalescence times using ancestral recombination graphs.Semantic proximity Read ↗

Interactive exploration of biobank-scale ancestral recombination graphs with LoraxSemantic proximity Read ↗

New methods for inference of local tree topologies with recombinant SNP sequences in populations.Semantic proximity Read ↗

genomicSimulation: fast R functions for stochastic simulation of breeding programs.Semantic proximity Read ↗

TMRCA is observable from the branch lengths of a coalescentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.