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Article

The association between parental BMI and offspring adiposity: A genetically informed analysis of trios.

PLoS genetics - 1 Aug 2025

Wright Liam, Shireby Gemma, Morris Tim T, Davies Neil M, Bann David

Abstract excerpt

BACKGROUND: Children with obesity are more likely to have parents with obesity than those without. Several environmental explanations have been proposed for this correlation, including foetal programming and parenting practices. However, body mass index (BMI) is a heritable trait; child-parent correlations may reflect direct inheritance of adiposity-related genes. There is some evidence that mothers' BMI...

Read the complete abstract on PubMed

Topics

Humans
Body Mass Index
Female
Adiposity
Male
Mendelian Randomization Analysis
Birth Weight

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Child

Adolescent

Child, Preschool

Fathers

Adult

Mothers

Obesity

United Kingdom

Pediatric Obesity

Multifactorial Inheritance

Parents

Source

Open in PubMed Open full text

Identifiers

PMID: 40763113
DOI: 10.1371/journal.pgen.1011775
PMCID: PMC12324121

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