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Parental and child genetic contributions to obesity traits in early life based on 83 loci validated in adults: the FAMILY study.

Pediatric obesity - 1 Mar 2018

Li A, Robiou-du-Pont S, Anand S S, Morrison K M, McDonald S D, Atkinson S A, Teo K K, Meyre D

Abstract excerpt

BACKGROUND: The genetic influence on child obesity has not been fully elucidated. OBJECTIVE: This study investigated the parental and child contributions of 83 adult body mass index (BMI)-associated single-nucleotide polymorphisms (SNPs) to obesity-related traits in children from birth to 5 years old. METHODS: A total of 1402 individuals were genotyped for 83 SNPs. An unweighted genetic risk score (GRS) was...

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Identifiers

PMID: 28008729
DOI: 10.1111/ijpo.12205

Genes

DMXL2

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