Article
Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight.
JAMA - 15 Mar 2016
Tyrrell Jessica, Richmond Rebecca C, Palmer Tom M, Feenstra Bjarke, Rangarajan Janani, Metrustry Sarah, Cavadino Alana, Paternoster Lavinia, Armstrong Loren L, De Silva N Maneka G, Wood Andrew R, Horikoshi Momoko, Geller Frank, Myhre Ronny, Bradfield Jonathan P, Kreiner-Møller Eskil, Huikari Ville, Painter Jodie N, Hottenga Jouke-Jan, Allard Catherine, Berry Diane J, Bouchard Luigi, Das Shikta, Evans David M, Hakonarson Hakon, Hayes M Geoffrey, Heikkinen Jani, Hofman Albert, Knight Bridget, Lind Penelope A, McCarthy Mark I, McMahon George, Medland Sarah E, Melbye Mads, Morris Andrew P, Nodzenski Michael, Reichetzeder Christoph, Ring Susan M, Sebert Sylvain, Sengpiel Verena, Sørensen Thorkild I A, Willemsen Gonneke, de Geus Eco J C, Martin Nicholas G, Spector Tim D, Power Christine, Järvelin Marjo-Riitta, Bisgaard Hans, Grant Struan F A, Nohr Ellen A, Jaddoe Vincent W, Jacobsson Bo, Murray Jeffrey C, Hocher Berthold, Hattersley Andrew T, Scholtens Denise M, Davey Smith George, Hivert Marie-France, Felix Janine F, Hyppönen Elina, Lowe William L, Frayling Timothy M, Lawlor Debbie A, Freathy Rachel M
Abstract excerpt
IMPORTANCE: Neonates born to overweight or obese women are larger and at higher risk of birth complications. Many maternal obesity-related traits are observationally associated with birth weight, but the causal nature of these associations is uncertain. OBJECTIVE: To test for genetic evidence of causal associations of maternal body mass index (BMI) and related traits with birth weight. DESIGN, SETTING, AND...
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