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Telomerase dynamics in stem cells: Unraveling the molecular nexus of cellular aging and regeneration

5 Aug 2025

Abstract excerpt

The expression levels of telomerase exhibit regulatory heterogeneity across different cell types and various biological stages of cell development. The expression of telomerase is dynamically regulated across cell types and developmental stages, with its activity predominantly determined by the abundance of its catalytic subunit, telomerase reverse transcriptase (TERT). Telomerase levels are typically high in the...

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PMID: 40759311
DOI: 10.1016/j.arr.2025.102853

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