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Article

Role of Telomerase in Hematopoietic Stem Cells

1 Jun 2005

Abstract excerpt

Studies in hematopoietic stem cell (HSC) biology are often focused on "self-renewal" and differentiation. Implicit in the word self-renewal is that the two daughter cells generated by a self-renewal division are identical to the parental cell. Strictly speaking, this is not possible because DNA is continuously damaged and repaired by DNA-repair mechanisms that are not 100% efficient. It is important to note that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 15958715
DOI: 10.1196/annals.1349.027

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