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From Serous Tubal Intraepithelial Carcinoma to Neuroendocrine Carcinoma: Molecular Dissection of a Rare Fallopian Tube Carcinoma.

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Mar 2026

Machuca-Aguado Jesús, Alfonso-Rosa Carmen, García-Escudero Antonio, Rubio-Garrido Francisco Javier, Trigo Inmaculada, Cano-Barbadillo Tatiana, McCluggage W Glenn

Abstract excerpt

Primary neuroendocrine carcinoma (NEC) of the fallopian tube is exceptionally rare, with only a small number of cases reported. We report an unusual case in a 77-yr-old woman where a fallopian tube was involved by serous tubal intraepithelial carcinoma (STIC), a small component of high-grade serous carcinoma (HGSC), and a predominant component of small cell neuroendocrine carcinoma (SCNEC). Molecular analysis of...

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Identifiers

PMID: 40758752
DOI: 10.1097/PGP.0000000000001127

Genes

CHEK2
PALB2
TP53

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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